|
|
| 锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷iPS细锟斤拷锟铰硷拷锟斤拷 |
|
锟秸憋拷锟叫撅拷锟斤拷员锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟芥病锟斤拷锟斤拷锟斤拷锟斤拷锟酵伙拷锟津，成癸拷锟斤拷实锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷锟斤拷锟秸碉拷锟洁功锟杰革拷细锟斤拷锟斤拷iPS细锟斤拷锟斤拷锟斤拷锟斤拷学锟斤拷说锟斤拷锟斤拷锟斤拷锟叫撅拷锟缴癸拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷“锟斤拷锟斤拷细锟斤拷”锟斤拷锟斤拷锟斤拷锟秸硷拷锟斤拷
锟秸憋拷锟斤拷锟斤拷锟斤拷学锟酵匡拷学锟斤拷锟斤拷锟斤拷锟剿伙拷锟斤拷10锟斤拷10锟秸凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟脚癸拷锟斤拷说锟斤拷锟斤拷前锟斤拷锟斤拷iPS细锟斤拷时锟斤拷锟斤拷要锟斤拷锟斤拷锟斤拷转录酶锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷Oct3/4锟斤拷Sox2锟斤拷Klf4锟斤拷c—Myc锟斤拷4锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷使锟矫诧拷锟斤拷锟斤拷锟斤拷锟叫匡拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟轿成★拷锟斤拷锟解，每锟斤拷实锟斤拷前锟斤拷要锟斤拷锟斤拷锟铰的诧拷锟斤拷锟斤拷锟藉，锟皆诧拷锟斤拷锟斤拷锟教猴拷实锟斤拷锟揭的癸拷锟斤拷要锟斤拷锟斤拷细锟斤拷舛硷拷璋拷锟絠PS细锟斤拷锟斤拷锟斤拷锟斤拷锟秸硷拷锟斤拷
锟斤拷锟斤拷锟斤拷学山锟斤拷锟斤拷锟街斤拷锟节碉拷锟叫撅拷小锟斤拷锟斤拷实锟斤拷锟斤拷使锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷“c—Myc”锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷Oct3/4锟斤拷Klf4锟斤拷Sox2锟斤拷锟斤拷然锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟酵憋拷锟斤拷锟绞碉拷锟斤拷锟斤拷锟教ワ拷锟斤拷锟轿革拷锟斤拷锟斤拷晒锟斤拷锟斤拷锟斤拷锟斤拷锟絠PS细锟斤拷锟斤拷
锟斤拷一锟斤拷锟斤拷实锟斤拷证实锟斤拷锟斤拷锟斤拷锟街凤拷锟斤拷锟斤拷锟斤拷锟斤拷iPS细锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷iPS细锟斤拷一锟斤拷锟杰分伙拷锟斤拷锟缴憋拷皮锟斤拷锟斤拷锟狡硷拷锟斤拷锟斤拷锟斤拷织锟饺讹拷锟斤拷细锟斤拷锟斤拷锟斤拷转锟斤拷效锟绞憋拷锟斤拷锟斤拷转录酶锟斤拷锟斤拷为锟斤拷锟斤拷要锟斤拷一些锟斤拷
锟叫撅拷锟斤拷员说锟斤拷锟斤拷一锟斤拷锟斤拷目锟斤拷锟斤拷锟斤拷锟阶拷锟叫э拷剩锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷路锟斤拷锟斤拷殉锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟较革拷锟斤拷锟斤拷锟斤拷锟絠PS细锟斤拷锟斤拷锟斤拷锟斤拷晒锟斤拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟窖э拷锟斤拷锟�Science锟斤拷锟斤拷志锟斤拷锟斤拷锟斤拷稀锟�
iPS细锟斤拷锟斤拷锟斤拷胎锟斤拷细锟斤拷锟酵筹拷锟斤拷锟较革拷锟斤拷锟轿拷芊只锟斤拷啥锟斤拷锟斤拷锟斤拷俸锟斤拷锟街革拷锟斤拷锟斤拷锟斤拷锟轿�“锟斤拷锟斤拷细锟斤拷”锟斤拷锟斤拷锟斤拷锟叫撅拷锟斤拷员锟斤拷为锟斤拷iPS细锟斤拷锟斤拷锟芥及锟斤拷锟斤拷锟斤拷锟解，锟斤拷锟斤拷锟斤拷医锟斤拷锟斤拷锟斤拷锟斤拷懈锟斤拷锟斤拷锟斤拷锟接︼拷锟角帮拷锟斤拷锟斤拷锟斤拷锟皆达拷锟斤拷禄锟斤拷锟� 钱铮ｏ拷
锟斤拷锟斤拷锟斤拷学锟斤拷锟斤拷
Science锟斤拷锟斤拷DOI: 10.1126/science.1164270锟斤拷Keisuke Okita锟斤拷Shinya Yamanaka锟斤拷
