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一锟斤拷锟斤拷锟斤拷锟斤拷锟街ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷系统锟斤拷慰锟斤拷锟绞讹拷鸩⒓锟绞憋拷锟斤拷锟斤拷锟斤拷锟接︼拷锟接︼拷缘锟斤拷锟斤拷锟饺撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷蔚锟斤拷锟斤拷锟斤拷锟较革拷锟斤拷识炔锟斤拷锟斤拷锟斤拷锟叫в︼拷锟斤拷樱锟斤拷锟斤拷锟叫э拷锟斤拷锟斤拷原锟斤拷锟酵憋拷锟斤拷锟斤拷锟斤拷嘶锟斤拷锟斤拷锟斤拷锟斤拷锟街拷员锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷约锟斤拷锟斤拷姆锟斤拷锟斤拷锟斤拷锟斤拷浅锟斤拷锟斤拷锟斤拷锟斤拷锟窖э拷壹锟轿拷锟阶拷突锟斤拷锟教斤拷锟斤拷锟斤拷锟揭拷锟窖э拷锟斤拷狻ｏ拷诠锟斤拷锟斤拷锟饺伙拷锟窖э拷锟斤拷锟斤拷卮锟斤拷锟侥匡拷锟�“973”锟斤拷目锟斤拷锟斤拷锟斤拷锟铰ｏ拷锟节讹拷锟斤拷医锟斤拷学锟斤拷锟斤拷学锟叫撅拷锟斤拷锟斤拷医学锟斤拷锟斤拷学锟斤拷锟斤拷锟截碉拷实锟斤拷锟斤拷锟斤拷锟轿诧拷雪锟斤拷院士锟酵革拷锟斤拷锟节帮拷锟斤拷锟铰★拷锟斤拷士锟斤拷锟斤拷锟斤拷锟斤拷锟缴的匡拷锟斤拷锟介，锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟节诧拷原锟斤拷碳锟斤拷筒锟斤拷锟斤拷锟饺撅拷锟斤拷锟铰诧拷锟斤拷锟斤拷锟斤拷锟截猴拷锟斤拷锟斤拷细锟斤拷锟斤拷锟接碉拷锟斤拷锟酵碉拷锟截伙拷锟狡★拷
锟矫伙拷锟狡的凤拷锟街ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷识锟斤拷锟斤拷锟斤拷慰锟斤拷锟斤拷锟皆拷锟饺撅拷锟斤拷锟街癸拷锟街拷锟斤拷锟斤拷锟斤拷锟斤拷呒锟斤拷锟斤拷姆锟斤拷锟斤拷锟揭诧拷锟斤拷锟斤拷锟斤拷诩锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷路锟斤拷锟斤拷锟斤拷锟狡★拷锟斤拷锟叫撅拷锟斤拷锟斤拷锟皆凤拷锟斤拷锟斤拷獠拷浞⒆拷锟斤拷锟斤拷鄣锟斤拷锟绞斤拷锟斤拷锟斤拷锟斤拷诮锟斤拷锟斤拷锟斤拷摹锟斤拷锟饺�—锟斤拷锟斤拷学锟斤拷(Nature Immunology)锟较★拷同锟节★拷锟斤拷然—锟斤拷锟斤拷学锟斤拷锟斤拷志锟斤拷3锟斤拷锟斤拷页锟斤拷篇锟斤拷锟斤拷锟戒发锟斤拷锟斤拷为锟斤拷锟斤拷细锟斤拷锟斤拷TLR锟脚猴拷转锟斤拷锟斤拷专锟斤拷锟斤拷锟桔ｏ拷锟斤拷锟节革拷锟斤拷锟叫撅拷锟斤拷锟斤拷锟侥达拷锟斤拷锟皆硷拷锟斤拷潜锟节碉拷应锟斤拷前锟斤拷锟斤拷锟斤拷锟剿高讹拷锟斤拷锟桔★拷
锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷突状细锟斤拷同锟斤拷锟斤拷锟斤拷锟斤拷系统锟斤拷“锟节憋拷”——锟斤拷原锟斤拷锟较革拷锟斤拷锟斤拷锟斤拷锟揭拷锟斤拷锟斤拷镁锟斤拷锟斤拷芄锟绞讹拷锟斤拷锟斤拷只锟斤拷锟斤拷锟斤拷源锟皆诧拷原锟藉并锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟节匡拷锟劫诧拷锟斤拷锟斤拷锟斤拷锟截猴拷锟斤拷氐锟较革拷锟斤拷锟斤拷拥锟酵憋拷锟斤拷庸锟斤拷锟斤拷锟斤拷锟皆拷锟斤拷锟斤拷息锟斤拷锟杰帮拷细锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷应锟斤拷锟斤拷锟斤拷锟斤拷锟皆拷濉ｏ拷锟斤拷锟斤拷锟斤拷细锟斤拷一锟斤拷失锟截讹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟接ｏ拷锟缴碉拷锟铰伙拷锟斤拷锟斤拷织锟斤拷锟斤拷锟剿ｏ拷锟斤拷锟斤拷锟秸凤拷锟斤拷症锟斤拷锟斤拷锟斤拷锟斤拷锟竭硷拷锟斤拷锟侥凤拷锟斤拷锟斤拷锟斤拷耍锟斤拷锟斤拷锟斤拷锟较革拷锟斤拷锟接︼拷锟斤拷锟教必讹拷锟杰碉拷锟斤拷细锟斤拷锟截ｏ拷锟斤拷锟斤拷目前为止锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷氐姆锟斤拷踊锟斤拷锟斤拷胁锟绞拷锟斤拷锟斤拷锟斤拷锟斤拷实锟斤拷锟斤拷锟斤拷员锟斤拷锟节达拷锟斤拷锟斤拷突状细锟斤拷锟饺碉拷锟斤拷锟斤拷识锟斤拷锟斤拷锟斤拷锟竭碉拷锟截的凤拷锟接伙拷锟狡碉拷锟叫撅拷锟斤拷锟斤拷锟叫撅拷锟斤拷锟斤拷锟叫ｏ拷锟桔察到锟斤拷锟斤拷酶SHP1锟斤拷锟斤拷缺锟捷碉拷小锟斤拷刹锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟街拷锟较革拷锟斤拷锟斤拷硬锟斤拷锟斤拷锟斤拷锟街拷锟斤拷锟斤拷锟斤拷锟斤拷呒锟斤拷锟斤拷锟截斤拷锟阶的凤拷锟斤拷锟斤拷锟斤拷趣锟斤拷锟角ｏ拷偶然锟斤拷锟街该伙拷锟斤拷缺锟斤拷小锟斤拷锟节诧拷原锟斤拷锟斤拷执碳锟斤拷筒锟斤拷锟斤拷锟饺撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟皆诧拷锟斤拷锟斤拷锟斤拷锟截ｏ拷锟斤拷示锟斤拷锟斤拷系统锟斤拷锟斤拷锟脚分憋拷锟斤拷馗锟斤拷锟斤拷睾锟斤拷锟街拷锟较革拷锟斤拷锟斤拷硬锟斤拷锟斤拷锟酵撅拷锟斤拷突锟斤拷啤锟�
锟斤拷实锟斤拷锟斤拷围锟斤拷锟斤拷一锟斤拷学锟斤拷锟斤拷展锟斤拷锟斤拷锟斤拷锟叫撅拷锟斤拷锟斤拷证锟斤拷锟斤拷SHP1锟斤拷锟斤拷通锟斤拷锟斤拷锟狡碉拷锟阶硷拷酶锟酵猴拷锟斤拷锟斤拷锟脚猴拷转锟斤拷通路锟斤拷锟斤拷锟斤拷锟斤拷症锟斤拷细锟斤拷锟斤拷锟接凤拷锟斤拷锟解，锟斤拷锟斤拷锟斤拷SHP1锟斤拷锟斤拷锟杰癸拷直锟接斤拷霞锟矫革拷锟斤拷锟絀RAK1锟侥硷拷酶锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟絀RAK1锟侥活化锟斤拷锟接讹拷锟斤拷锟斤拷锟絀RAK1锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟节革拷锟斤拷锟斤拷锟脚猴拷通路锟斤拷锟斤拷锟斤拷锟斤拷锟矫ｏ拷使锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷突状细锟斤拷锟斤拷识锟斤拷原锟斤拷锟斤拷锟节革拷锟斤拷锟斤拷锟斤拷锟接ｏ拷锟斤拷锟斤拷SHP1锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟接诧拷锟斤拷锟斤拷同时锟斤拷锟皆促斤拷锟斤拷锟斤拷锟截的凤拷锟节ｏ拷锟接讹拷锟斤拷锟斤拷锟节伙拷锟斤拷锟斤拷锟斤拷锟皆拷锟斤拷同时锟街匡拷锟斤拷锟斤拷锟斤拷症锟斤拷锟斤拷锟斤拷锟斤拷锟竭硷拷锟斤拷锟侥凤拷锟斤拷锟斤拷
锟斤拷雪锟斤拷实锟斤拷锟斤拷锟斤拷锟斤拷2006锟斤拷锟斤拷锟斤拷锟斤拷学锟斤拷锟节匡拷锟斤拷锟斤拷锟竭★拷锟斤拷Immunity锟斤拷锟较凤拷锟斤拷锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷要锟斤拷锟斤拷锟斤拷酶锟斤拷锟斤拷SHP2锟斤拷锟节诧拷原锟斤拷锟秸碉拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟截的碉拷锟斤拷锟斤拷锟矫ｏ拷锟斤拷耍锟斤拷锟绞碉拷锟斤拷锟斤拷纸锟揭伙拷锟教斤拷锟斤拷锟絊HP1锟斤拷SHP2锟侥癸拷系锟斤拷锟斤拷锟斤拷SHP2锟杰癸拷锟斤拷锟斤拷锟斤拷锟絊HP1锟斤拷锟节革拷锟斤拷锟截诧拷锟斤拷锟斤拷锟斤拷强效应锟斤拷锟剿斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥凤拷锟斤拷锟皆硷拷锟斤拷氐姆锟斤拷踊锟斤拷锟斤拷芯锟轿拷锟斤拷锟较革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷氐锟斤拷藕锟阶拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷烁锟斤拷锟饺拷锟斤拷锟斤拷识锟斤拷锟矫斤拷锟斤拷锟斤拷诨锟斤拷锟斤拷锟斤拷锟较低筹拷锟斤拷锟斤拷锟绞讹拷锟斤拷锟斤拷锟皆硷拷锟斤拷锟斤拷细锟斤拷锟斤拷锟杰碉拷锟截碉拷锟叫撅拷锟斤拷锟斤拷锟斤拷碌姆锟斤拷锟揭参拷锟斤拷锟斤拷锟斤拷锟斤拷锟饺撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷约锟斤拷锟斤拷锟截斤拷锟阶碉拷锟斤拷药锟斤拷疲锟斤拷峁╋拷锟斤拷碌陌斜锟斤拷思路锟斤拷锟斤拷锟斤拷源锟斤拷锟斤拷学时锟斤拷 锟斤拷锟斤拷 肖锟轿ｏ拷
锟斤拷锟斤拷锟斤拷然—锟斤拷锟斤拷学锟斤拷(
Nature Immunology)锟斤拷9, 542 - 550 (2008) 锟斤拷Huazhang An, Xuetao Cao锟斤拷
