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锟捷★拷锟斤拷然锟斤拷锟斤拷站锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟教诧拷锟酵帮拷血锟斤拷锟斤拷锟斤拷锟斤拷锟节斤拷锟斤拷锟斤拷锟斤拷锟较革拷锟斤拷锟街诧拷锟斤拷锟斤拷锟斤拷锟斤拷旨锟斤拷锟斤拷锟斤拷锟�“锟斤拷锟斤拷”锟斤拷锟斤拷植锟斤拷锟矫革拷细锟斤拷锟斤拷源锟斤拷一位锟皆帮拷锟教诧拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥撅拷锟斤拷锟竭★拷锟斤拷锟斤拷2锟斤拷时锟斤拷锟饺ワ拷耍锟斤拷锟绞癸拷锟斤拷锟斤拷锟斤拷锟矫伙拷锟绞癸拷每锟斤拷锟阶硷拷锟斤拷锟揭┢凤拷锟揭裁伙拷锟斤拷俜锟斤拷锟紿IV锟斤拷锟斤拷锟斤拷
锟铰癸拷医锟斤拷锟斤拷2008锟斤拷11锟铰撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟角的凤拷锟街ｏ拷锟斤拷锟斤拷时锟斤拷锟叫撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟酵拷锟斤拷锟斤拷椴拷锟斤拷辗锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷摹锟斤拷锟接拷锟斤拷锟揭窖э拷锟街撅拷锟斤拷锟�New England Journal of Medicine锟斤拷锟较★拷
锟轿何对伙拷锟狡凤拷应锟斤拷锟窖的帮拷血锟斤拷锟斤拷锟竭讹拷应锟斤拷锟杰癸拷锟斤拷锟斤拷植锟斤拷医锟斤拷锟斤拷锟斤拷寻锟斤拷锟斤拷锟斤拷锟斤拷叩锟阶拷锟斤拷锟斤拷希锟斤拷锟轿拷锟斤拷锟窖帮拷液锟斤拷锟斤拷锟斤拷停锟斤拷锟阶硷拷锟斤拷锟斤拷锟斤拷锟街诧拷锟斤拷锟斤拷锟�
锟斤拷锟斤拷锟铰癸拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭窖г猴拷锟紺harité Universitätsmedizin锟斤拷血液学锟斤拷Gero Hütter锟斤拷锟斤拷锟侥癸拷锟斤拷锟斤拷一锟斤拷墓锟斤拷锟斤拷锟街诧拷纸锟斤拷锟揭伙拷锟斤拷锟紿ütter锟斤拷锟斤拷锟斤拷专锟斤拷锟斤拷锟教诧拷锟斤拷学锟竭ｏ拷锟斤拷锟角碉拷锟斤拷锟斤拷识锟斤拷锟斤拷锟斤拷一位锟斤拷锟斤拷锟斤拷要锟斤拷锟叫癸拷锟斤拷锟斤拷植时锟斤拷锟斤拷锟斤拷锟斤拷10锟斤拷锟斤拷锟角帮拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭黄拷锟斤拷模锟斤拷锟斤拷锟斤拷锟揭恍╋拷司锟斤拷锟斤拷锟斤拷锟斤拷锟脚达拷锟斤拷锟届，使锟斤拷锟角对帮拷锟教诧拷锟斤拷锟叫抵匡拷锟斤拷锟斤拷
锟斤拷锟街憋拷锟斤拷锟斤拷指CCR5锟斤拷锟斤拷锟斤拷一小锟斤拷缺失锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷澹拷锟斤拷滩锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟轿狢D4+ T细锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟叫达拷约1%锟斤拷欧锟斤拷锟剿匡拷锟斤拷CCR5锟斤拷锟斤拷锟饺拷锟�2锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟街憋拷锟届，锟斤拷使锟斤拷锟斤拷些锟剿猴拷锟窖革拷染锟斤拷锟教诧拷锟斤拷锟斤拷锟斤拷锟紿ütter锟斤拷锟斤拷锟斤拷锟斤拷缺锟斤拷CCR5锟斤拷锟斤拷锟较革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟侥伙拷锟斤拷锟斤拷锟斤拷也锟斤拷锟酵诧拷锟斤拷锟斤拷么锟斤拷锟阶革拷染锟斤拷锟教诧拷锟斤拷锟剿★拷
Hütter锟节德癸拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟轿拷锟斤拷锟斤拷锟斤拷锟斤拷业锟斤拷锟�80锟斤拷锟斤拷锟绞碉拷锟斤拷锟酵ｏ拷锟斤拷锟斤拷61锟脚癸拷锟斤拷锟斤拷锟斤拷弑锟街な碉拷锟斤拷锟斤拷锟斤拷锟紺CR5锟斤拷锟届，锟斤拷2007锟斤拷2锟斤拷Hütter锟皆伙拷锟竭斤拷锟斤拷锟斤拷锟斤拷一锟斤拷植锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷夕锟斤拷锟斤拷锟角达拷学锟斤拷锟教诧拷锟叫撅拷锟斤拷James Riley锟斤拷示锟斤拷锟斤拷锟杰碉拷锟斤拷锟斤拷为止只锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷羌锟斤拷呒锟街碉拷摹锟斤拷锟剿碉拷锟�“锟斤拷锟结供锟剿筹拷锟斤拷证锟捷憋拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷写蟛糠锟较革拷锟斤拷锟斤拷卸园锟斤拷滩锟斤拷牡挚锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟杰癸拷锟街匡拷锟斤拷锟斤拷锟斤拷”
Hütter锟斤拷锟绞撅拷锟揭伙拷锟揭斤拷锟斤拷锟阶硷拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷滩锟斤拷锟斤拷锟斤拷锟斤拷缘陌锟窖拷锟斤拷锟斤拷私锟斤拷锟酵拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷饨拷堑诙锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟角撅拷锟杰匡拷锟斤拷锟斤拷锟斤拷锟�
锟斤拷么锟斤拷锟竭撅拷锟斤拷锟斤拷没锟叫憋拷锟斤拷锟斤拷锟截ｏ拷锟解还说锟斤拷锟矫ｏ拷锟斤拷锟杰革拷锟斤拷锟斤拷锟竭达拷约2锟斤拷时锟斤拷没锟叫筹拷锟街革拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫匡拷锟杰诧拷锟斤拷锟斤拷然锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭诧拷锟斤拷锟角憋拷锟斤拷锟揭斤拷锟斤拷薹锟斤拷锟斤拷锟斤拷细锟斤拷锟节ｏ拷锟斤拷锟斤拷锟皆诧拷锟斤拷锟斤拷锟斤拷锟较革拷锟斤拷锟�
锟斤拷锟解，锟斤拷锟斤拷一锟洁艾锟教诧拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷CCR5锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷锟洁病锟斤拷通锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷系统锟侥诧拷锟斤拷锟斤拷锟较筹拷锟街ｏ拷锟斤拷锟斤拷锟斤拷锟角匡拷锟斤拷锟斤拷锟秸伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟节凤拷锟杰★拷
锟斤拷锟斤拷确锟斤拷锟斤拷锟角ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷滩锟斤拷锟斤拷锟斤拷锟斤拷缘锟斤拷丝锟斤拷虏锟斤拷锟皆革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟狡凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷植锟斤拷一锟斤拷锟斤拷锟秸ｏ拷锟斤拷锟斤拷锟斤拷锟侥匡拷锟斤拷转录锟斤拷锟斤拷药锟斤拷锟狡凤拷锟斤拷说锟斤拷锟斤拷使锟斤拷锟角碉拷药锟斤拷母锟斤拷锟斤拷茫锟斤拷锟斤拷锟斤拷锟街诧拷姆锟斤拷栈锟斤拷锟揭拷锟斤拷锟揭恍╋拷锟斤拷诮锟斤拷芄锟斤拷锟斤拷锟街睬帮拷锟斤拷锟斤拷锟揭拷锟斤拷锟揭╋拷锟酵凤拷锟戒处锟斤拷锟斤拷杀锟斤拷锟皆硷拷锟斤拷锟斤拷血锟斤拷细锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷锟叫ｏ拷锟斤拷锟剿硷拷锟斤拷锟杰碉拷锟斤拷染锟斤拷锟斤拷锟斤拷锟斤拷锟秸诧拷锟剿碉拷锟斤拷锟藉还锟叫匡拷锟杰讹拷锟斤拷锟斤拷植锟侥革拷细锟斤拷锟斤拷锟斤拷锟斤拷锟届。
锟斤拷一些药锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷频锟斤拷锟斤拷茫锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭╋拷锟剿撅拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟紺CR5锟斤拷锟狡硷拷锟斤拷锟斤拷为maraviroc锟斤拷锟窖憋拷锟斤拷准锟斤拷锟斤拷锟斤拷锟斤拷欧锟斤拷使锟矫★拷锟斤拷锟斤拷锟斤拷司锟斤拷忙锟斤拷锟叫凤拷锟斤拷锟斤拷一锟斤拷锟侥帮拷锟斤拷CCR5锟斤拷药品锟斤拷
锟斤拷锟揭碉拷锟角ｏ拷maraviroc锟斤拷锟斤拷锟斤拷锟斤拷全锟斤拷止锟斤拷锟教诧拷锟斤拷锟襟定碉拷CCR5锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷药锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷转录锟斤拷锟斤拷药品一锟斤拷锟斤拷锟绞癸拷谩锟絉iley锟斤拷示锟斤拷“锟斤拷锟斤拷锟较帮拷锟教诧拷锟斤拷锟斤拷锟揭碉拷一些锟斤拷锟斤拷锟狡癸拷药锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟紺CR5”锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷说锟斤拷锟斤拷锟教诧拷锟斤拷锟斤拷锟斤拷锟杰伙拷锟斤拷锟斤拷锟斤拷药锟斤，锟斤拷锟斤拷锟杰绑定碉拷CCR5锟斤拷锟斤拷锟斤拷锟斤拷锟街ｏ拷锟斤拷药锟斤拷却锟斤拷锟叫★拷
锟斤拷锟斤拷锟叫撅拷锟斤拷员锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷品锟斤拷锟斤拷锟饺拷锟街笴CR5锟侥诧拷锟斤拷锟斤拷锟斤拷锟界，Riley锟斤拷去锟斤拷锟斤拷一锟揭筹拷为Sangamo BioSciences锟斤拷锟斤拷锟斤技锟斤拷锟斤拷司锟斤拷锟斤拷锟斤拷锟斤拷确锟斤拷锟矫癸拷司一锟斤拷锟斤拷锟斤拷锟矫筹拷目锟斤拷锟斤拷锟侥硷拷锟斤拷锟角凤拷锟斤拷锟斤拷锟斤拷锟矫筹拷CCR5锟斤拷锟斤拷Sangamo锟斤拷司锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷司锟窖撅拷锟斤拷始锟劫达拷I锟斤拷锟斤拷锟介，锟斤拷一锟斤拷锟介将锟斤拷锟斤拷锟狡筹拷锟斤拷锟斤拷锟斤拷T细锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷锟矫筹拷CCR5锟斤拷锟津，诧拷锟斤拷锟斤拷锟斤拷锟揭伙拷亩锟斤拷锟斤拷锟较革拷锟斤拷锟斤拷锟阶拷氩★拷锟斤拷锟斤拷凇锟斤拷锟揭伙拷锟斤拷锟斤拷歉锟斤拷锟斤拷锟洁技锟斤拷锟斤拷全锟皆讹拷锟斤拷锟斤拷效锟侥碉拷一锟斤拷锟斤拷锟斤拷锟揭诧拷锟斤拷锟竭碉拷未锟杰改讹拷锟斤拷T细锟斤拷锟斤拷锟斤拷锟结被锟捷毁★拷锟斤拷锟斤拷学锟斤拷 锟斤拷锟斤拷/锟斤拷锟诫）
锟斤拷锟斤拷锟斤拷英锟斤拷锟斤拷医学锟斤拷志锟斤拷锟斤拷NEJM锟斤拷锟斤拷Volume 360:692-698锟斤拷Gero Hütter锟斤拷Eckhard Thiel锟斤拷
锟斤拷锟斤拷锟侥讹拷锟斤拷英锟侥ｏ拷
