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锟斤拷1锟斤拷28锟秸★拷锟斤拷锟斤拷医学协锟斤拷锟节匡拷锟斤拷锟斤拷JAMA锟斤拷锟较碉拷一锟斤拷锟叫撅拷锟斤拷露锟斤拷锟斤拷锟斤拷某些锟脚达拷锟斤拷锟斤拷募锟斤拷猿锟斤拷馨锟较革拷锟斤拷园锟窖拷锟斤拷幕锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷牟锟斤拷锟斤拷锟饺ｏ拷锟斤拷锟角对匡拷锟斤拷锟斤拷锟狡伙拷锟叫诧拷同锟侥凤拷应锟斤拷
锟斤拷锟斤拷锟斤拷锟铰的憋拷锟斤拷锟斤拷锟较ｏ拷锟斤拷锟狡的硷拷锟皆筹拷锟杰帮拷细锟斤拷锟皆帮拷血锟斤拷锟斤拷ALL锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟窖撅拷锟斤拷1960锟斤拷锟斤拷牟锟斤拷锟�10%锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷80%锟斤拷锟较ｏ拷锟斤拷锟斤拷锟斤拷些锟斤拷锟斤拷锟斤拷锟斤拷锟狡的凤拷应却锟斤拷锟斤拷锟斤拷锟洁当锟斤拷锟斤拷锟斤拷薹锟斤拷锟斤拷偷母锟斤拷锟斤拷锟届。
St. Jude锟斤拷童锟叫撅拷医院锟斤拷Jun J. Yang锟斤拷锟斤拷同锟脚匡拷展锟斤拷一锟斤拷锟叫撅拷锟斤拷旨锟节凤拷锟街匡拷锟斤拷影锟斤拷ALL锟斤拷锟狡凤拷应锟斤拷锟斤拷些锟脚达拷锟斤拷锟接★拷锟叫撅拷锟斤拷员锟斤拷2锟介患锟竭ｏ拷锟斤拷锟斤拷487锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷平锟斤拷锟斤拷锟绞憋拷锟斤拷锟斤拷锟角斤拷锟斤拷锟剿碉拷锟斤拷锟斤拷锟斤拷锟教拷裕锟絊NPs锟斤拷锟斤拷锟脚达拷锟斤拷锟届）锟斤拷锟斤拷锟斤拷锟节凤拷锟斤拷锟斤拷锟斤拷锟斤拷微小锟斤拷锟斤拷锟斤拷锟戒（MRD锟斤拷之锟斤拷锟斤拷锟斤拷锟皆ｏ拷锟斤拷些锟斤拷童锟斤拷锟斤拷锟铰斤拷锟斤拷匣锟斤拷锟紸LL锟斤拷锟斤拷些锟斤拷锟斤拷锟斤拷锟斤拷 1994锟斤拷锟斤拷2006锟斤拷锟节间被锟斤拷锟缴碉拷锟叫撅拷之锟叫的ｏ拷锟斤拷锟斤拷锟角碉拷锟斤拷锟斤拷锟斤拷锟绞憋拷锟斤拷锟斤拷锟�2006锟疥。
锟叫撅拷锟斤拷员锟斤拷锟街ｏ拷锟斤拷锟斤拷2锟斤拷锟叫ｏ拷锟斤拷102锟斤拷SNPs锟斤拷MRD锟斤拷亍锟斤拷锟斤拷锟�102锟斤拷SNPs锟节撅拷锟斤拷锟斤拷锟结、锟皆憋拷锟斤拷锟绞憋拷馨锟较革拷锟斤拷锟揭伙拷锟斤拷锟斤拷偷锟窖合革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷约锟紸LL锟斤拷锟酵碉拷校锟斤拷之锟斤拷锟斤拷然锟斤拷MRD锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷浴锟斤拷锟�102锟斤拷SNPs锟叫ｏ拷锟斤拷21锟斤拷锟斤拷眉锟斤拷锟斤拷锟窖猴拷锟窖э拷裕锟斤拷锟斤拷锟窖猴拷锟截的ｏ拷锟侥革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷浴锟斤拷锟�102锟斤拷SNPs锟叫ｏ拷锟斤拷21锟街伙拷锟诫抗锟斤拷血锟斤拷锟斤拷药锟斤处锟矫撅拷锟斤拷锟斤拷锟斤拷裕锟斤拷锟斤拷锟酵拷锟斤拷峤玀RD锟侥革拷锟斤拷锟斤拷锟斤拷锟斤拷药锟斤拷哟锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷芯锟斤拷锟皆憋拷锟斤拷郑锟斤拷泻芨弑锟斤拷锟斤拷锟�63/102 SNPs [ 61.7% ]锟斤拷锟斤拷SNPs锟斤拷锟斤拷锟斤拷锟节的凤拷应锟斤拷锟斤拷锟斤拷锟侥凤拷锟秸ｏ拷锟津抗帮拷血锟斤拷药锟斤拷拇锟斤拷镁锟斤拷泄锟斤拷锟斤拷浴锟�
锟斤拷锟铰碉拷锟斤拷锟竭得筹拷锟斤拷锟桔ｏ拷“锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟侥猴拷锟斤拷锟脚达拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭╋拷锟侥凤拷应锟斤拷锟斤拷锟脚关硷拷锟皆碉拷锟斤拷锟矫ｏ拷锟斤拷锟斤拷锟角的斤拷锟斤拷锟绞撅拷锟斤拷锟斤拷叩锟斤拷锟斤拷锟斤拷锟斤拷糯锟斤拷锟斤拷锟揭诧拷锟接帮拷炜癸拷锟斤拷锟斤拷频锟叫э拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥凤拷锟斤拷锟斤拷使锟斤拷锟角凤拷锟斤拷锟铰的讹拷锟揭匡拷锟杰碉拷药锟斤拷锟脚达拷学锟侥憋拷锟届。锟斤拷锟斤拷目前强锟斤拷锟斤拷锟斤拷锟斤拷锟脚达拷锟斤拷锟斤拷之锟解，锟斤拷锟街憋拷锟斤拷锟斤拷锟斤拷锟轿达拷锟酵拷锟斤拷锟斤拷锟角匡拷锟斤拷锟斤拷药锟斤传锟斤拷锟皆克凤拷锟斤拷锟斤拷锟脚达拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷频锟斤拷锟斤拷锟�”锟斤拷(
JAMA. 2009;301[4]:393-403)锟斤拷锟斤拷源锟斤拷EurekAlert! 锟斤拷锟侥版）
锟斤拷锟斤拷锟斤拷锟斤拷医学协锟斤拷锟节匡拷锟斤拷锟斤拷
JAMA锟斤拷锟斤拷301(4):393-403锟斤拷Jun J. Yang锟斤拷Mary V. Relling锟斤拷
锟斤拷锟斤拷锟侥讹拷锟斤拷英锟侥ｏ拷
JAMA锟斤拷锟斤拷锟斤拷锟斤拷摘要
