|
|
| 锟斤拷锟街讹拷锟皆斤拷锟斤拷锟斤拷锟斤拷锟截硷拷锟斤拷锟斤拷突锟斤拷 |
|
锟斤拷锟斤拷锟脚克达拷学医学锟斤拷锟侥猴拷约锟斤拷锟斤拷锟秸斤拷斯锟斤拷学锟侥匡拷学锟斤拷锟斤拷锟狡ｏ拷锟斤拷锟角凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥讹拷锟皆斤拷锟斤拷锟斤拷锟斤拷锟斤拷丶锟斤拷幕锟斤拷锟酵伙拷洌拷锟皆讹拷锟皆斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷虾锟斤拷锟斤拷凭锟斤拷锟斤拷卮锟斤拷锟斤拷澹拷锟街拷芯锟斤拷锟斤拷锟揭伙拷锟斤拷麓锟斤拷凇锟斤拷泄锟斤拷芯锟斤拷锟斤拷锟斤拷诮锟斤拷粘锟斤拷锟侥★拷锟斤拷英锟斤拷锟斤拷医学锟斤拷志锟斤拷锟较★拷
锟斤拷锟斤拷锟斤拷为锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷酶锟斤拷IsocitrateDehydrogenase锟斤拷IDH锟斤拷锟侥伙拷锟斤拷锟斤拷一锟斤拷锟铰陈达拷谢锟斤拷锟斤拷锟叫的关硷拷酶锟斤拷锟脚克达拷学锟斤拷锟斤拷学系锟斤拷锟斤拷锟斤拷锟街猴拷锟斤拷锟斤拷锟诫）锟脚讹拷通锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷筛选锟斤拷锟斤拷锟斤拷IDH1锟斤拷IDH2锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷突锟戒不锟斤拷锟节讹拷锟皆斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟节筹拷锟街ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷也锟斤拷锟节★拷锟斤拷一位锟斤拷锟斤拷锟竭★拷锟脚克达拷学锟斤拷锟斤拷斯锟斤拷·锟睫诧拷锟斤拷·锟斤拷斯锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟轿达拷锟斤拷锟�·锟饺革拷锟斤拷说锟斤拷“锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷IDH锟斤拷锟斤拷锟角讹拷锟皆斤拷锟斤拷锟斤拷锟斤拷锟斤拷原始锟侥伙拷锟斤拷突锟戒，锟斤拷锟斤拷锟斤拷锟斤拷织锟斤拷每锟斤拷锟斤拷锟斤拷锟较革拷锟斤拷诙锟斤拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟酵伙拷洹�”
锟斤拷锟揭ｏ拷锟叫撅拷锟斤拷员锟斤拷锟街ｏ拷IDH1锟斤拷IDH2锟斤拷锟斤拷突锟斤拷只锟斤拷锟斤拷锟节讹拷锟皆斤拷锟斤拷锟斤拷锟叫ｏ拷锟节诧拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷织细锟斤拷锟斤拷锟斤拷没锟叫ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫撅拷锟斤拷丶锟斤拷姆锟斤拷锟街伙拷锟斤拷锟轿拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷撇锟斤拷锟斤拷锟斤拷澹诧拷趴锟斤拷锟绞碉拷帧锟�
IDH1锟斤拷IDH2锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟街伙拷锟斤拷锟侥和达拷锟斤拷锟侥讹拷锟斤拷锟皆斤拷锟斤拷母细锟斤拷锟斤拷锟斤拷GBM锟斤拷锟斤拷GBM锟斤拷锟斤拷锟斤拷锟侥讹拷锟斤拷锟今经斤拷锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷锟洁。锟街猴拷锟斤拷锟斤拷说锟斤拷IDH锟斤拷锟斤拷确实锟竭凤拷锟剿帮拷症锟斤拷锟斤拷IDH1锟斤拷IDH2突锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷为锟劫达拷锟斤拷锟街革拷耄拷锟斤拷诓锟酵拷慕锟斤拷锟斤拷锟斤拷谢锟斤拷锟斤拷锟街诧拷同锟斤拷锟斤拷丝锟斤拷院锟斤拷锟斤拷锟斤拷锟斤拷锟街伙拷锟叫革拷锟街斤拷锟斤拷锟斤拷锟侥诧拷锟剿ｏ拷锟斤拷锟斤拷医师锟斤拷锟捷诧拷同锟侥诧拷锟斤拷锟斤拷懈锟斤拷寤拷锟斤拷啤锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷俅锟斤拷锟较碉拷实锟绞诧拷锟斤拷锟斤拷也锟斤拷强锟斤拷锟斤拷锟斤拷IDH突锟戒集锟斤拷锟斤拷同一位锟斤拷,只锟斤拷要锟斤拷锟絀DH突锟斤拷锟斤拷锟节碉拷DNA片锟轿斤拷锟叫诧拷锟津，就匡拷锟斤拷锟叫断讹拷锟皆斤拷锟斤拷锟斤拷锟斤拷锟侥革拷锟斤拷锟斤拷锟斤拷锟斤拷佣锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟皆碉拷锟斤拷锟狡★拷锟斤拷锟斤拷源锟斤拷锟狡硷拷锟秸憋拷 锟斤拷霞锟斤拷
锟斤拷锟斤拷锟斤拷英锟斤拷锟斤拷医学锟斤拷志锟斤拷锟斤拷
NEJM锟斤拷锟斤拷Volume 360:765-773锟斤拷Hai Yan锟斤拷Darell D. Bigner锟斤拷
