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锟斤拷锟斤拷锟斤拷学锟斤拷锟斤拷锟斤拷学学院锟脚达拷茂锟斤拷师锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟�“A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function” 锟斤拷4锟斤拷9锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭匡拷学院院锟斤拷锟斤拷锟斤拷PNAS锟斤拷锟斤拷锟斤拷锟斤拷
锟脚达拷茂锟斤拷师实锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷郑锟斤拷锟紸urora-A锟斤拷锟阶硷拷酶锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷谢锟斤拷锟斤拷锟酵伙拷洌拷锟斤拷锟绞碉拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷准锟矫窤urora-B锟斤拷转锟戒，锟接讹拷为锟斤拷锟斤拷锟绞斤拷锟斤拷锟斤拷锟铰碉拷锟截碉拷锟阶诧拷锟斤拷锟侥匡拷锟斤拷模式锟结供锟斤拷锟铰碉拷证锟捷★拷锟斤拷锟斤拷锟侥的碉拷一锟斤拷锟竭革拷锟斤拷锟斤拷为锟脚达拷茂锟斤拷锟斤拷指锟斤拷锟斤拷锟斤拷锟疥级锟斤拷士锟叫撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷2004锟疥本锟狡憋拷业锟节憋拷锟斤拷锟斤拷学锟斤拷锟斤拷锟斤拷锟狡硷拷锟斤拷锟斤拷锟脚达拷茂锟斤拷锟斤拷锟叫撅拷锟斤拷锟斤拷硕锟斤拷锟斤拷锟斤拷锟叫撅拷锟斤拷锟斤拷
Aurora锟斤拷酶锟斤拷锟斤拷锟皆憋拷锟较革拷锟斤拷锟街筹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷械牡锟斤拷锟斤拷锟斤拷樱锟斤拷锟揭拷锟斤拷锟紸urora-A锟斤拷Aurora-B锟斤拷Aurora-C锟斤拷锟斤拷锟斤拷员锟斤拷锟矫硷拷锟斤拷锟皆憋拷幕锟斤拷锟酵伙拷锟酵憋拷锟斤拷失锟斤拷锟斤拷锟结导锟斤拷细锟斤拷锟斤拷锟斤拷锟筋动锟斤拷锟斤拷锟斤拷锟斤拷锟揭★拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷锟劫帮拷锟斤拷直锟斤拷锟斤拷锟斤拷锟窖筹拷锟斤拷锟斤拷前锟斤拷锟劫帮拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷细锟斤拷锟叫ｏ拷Aurora锟斤拷酶锟侥憋拷锟斤拷锟斤拷锟酵硷拷酶锟斤拷锟皆伙拷锟斤拷锟斤拷锟斤拷锟竭★拷Aurora-A锟斤拷Aurora-B锟斤拷Aurora锟斤拷酶锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷要锟斤拷锟斤拷锟斤拷锟斤拷员锟斤拷锟斤拷锟角的碉拷锟斤拷锟斤拷锟斤拷同源锟皆达到70%锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷殖锟斤拷锟斤拷锟斤拷却锟斤拷锟街筹拷锟斤拷锟斤拷锟斤拷全锟斤拷同锟侥讹拷位锟酵癸拷锟杰★拷锟斤拷锟斤拷锟窖э拷锟斤拷锟斤拷锟斤拷锟窖э拷叩墓惴猴拷锟阶拷锟斤拷锟揭恢泵伙拷械玫锟斤拷锟斤拷锟斤拷
锟脚达拷茂锟斤拷锟斤拷锟届导锟斤拷锟叫撅拷锟介发锟街ｏ拷锟斤拷Aurora-A锟斤拷198位锟斤拷锟斤拷锟斤拷谢锟斤拷锟斤拷劝锟斤拷幔┩伙拷锟斤拷Aurora-B锟斤拷应位锟斤拷陌锟斤拷锟斤拷锟叫伙拷锟斤拷锟届冬锟斤拷锟斤拷锟斤拷锟襟，撅拷锟斤拷锟斤拷细锟斤拷锟斤拷位锟酵癸拷锟斤拷锟斤拷实锟斤拷Aurora-A锟斤拷Aurora-B锟斤拷转锟戒。锟斤拷锟角伙拷锟节伙拷锟斤拷锟较讹拷锟斤拷一转锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷丶锟斤拷陌锟斤拷锟斤拷锟叫伙拷锟侥诧拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷水锟斤拷锟斤拷锟斤拷锟紸urora-A锟斤拷Aurora-B之锟斤拷薮锟斤拷锟斤拷锟斤拷锟揭拷锟斤拷亍锟斤拷锟较革拷锟斤拷校锟紸urora-A锟斤拷Aurora-B锟节讹拷位锟酵癸拷锟斤拷锟较的诧拷同锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟角碉拷锟斤拷锟斤拷锟斤拷维锟结构锟较碉拷细微锟斤拷锟届。锟斤拷锟斤拷位锟姐氨锟斤拷锟斤拷谢锟斤拷牟锟酵拷锟斤拷锟斤拷锟斤拷锟紸urora-A锟斤拷Aurora-B锟诫不同锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟洁互锟斤拷锟矫ｏ拷锟接讹拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟节的诧拷同位锟矫ｏ拷锟斤拷锟斤拷锟诫不同锟斤拷细锟斤拷锟脚号碉拷锟斤拷通路锟斤拷锟斤拷一锟斤拷锟斤拷为锟斤拷锟斤拷Aurora-A锟斤拷Aurora-B锟斤拷细锟斤拷锟斤拷殖锟斤拷锟斤拷锟叫的碉拷锟斤拷模式锟皆硷拷锟斤拷锟斤拷锟节斤拷锟斤拷锟较碉拷锟斤拷系锟结供锟斤拷锟铰碉拷锟斤拷识锟斤拷锟斤拷锟斤拷源锟斤拷锟斤拷锟斤拷锟斤拷学锟斤拷
