英国伦敦卫生与热带医学院Peter Piot等研究人员疫苗免疫的重要进展与尚未完成的使命进行了总结性回顾。2019年11月7日，国际学术期刊《自然》发表了这一综述。

研究人员表示，预防传染病的疫苗改变了人类的未来，每年挽救了成千上万的儿童和成年人的生命，并为整个社会带来了重大利益。

研究人员发现，国家和国家以下一级区域的疫苗接种覆盖率差异很大，主要的未满足需求仍然存在。尽管科学进展为新型疫苗开辟了令人振奋的前景，但是从发现到可持续实施的途径可能漫长而艰难，即从融资、开发和许可到计划实施和公众接受。免疫是卫生方面的最佳投资之一，应继续作为研究、工业、公共卫生和社会的重点。

附：英文原文

Title: Immunization: vital progress, unfinished agenda

Author: Peter Piot, Heidi J. Larson, Katherine L. OBrien, John Nkengasong, Edmond Ng, Samba Sow, Beate Kampmann

Issue&Volume: 2019-11-06

Abstract: Vaccination against infectious diseases has changed the future of the human species, saving millions of lives every year, both children and adults, and providing major benefits to society as a whole. Here we show, however, that national and sub-national coverage of vaccination varies greatly and major unmet needs persist. Although scientific progress opens exciting perspectives in terms of new vaccines, the pathway from discovery to sustainable implementation can be long and difficult, from the financing, development and licensing to programme implementation and public acceptance. Immunization is one of the best investments in health and should remain a priority for research, industry, public health and society. An overview of the effects of vaccines on global morbidity and mortality, vaccine safety issues, and the hurdles involved in proceeding from vaccine discovery to successful implementation.

DOI: 10.1038/s41586-019-1656-7

Source:

https://www.nature.com/articles/s41586-019-1656-7