韩国成均馆大学Tae-il Kim及其研究小组受角质层垫启发，研发出几乎动态无噪的生物电子学选择性频率阻尼器。相关论文于2022年5月6日发表于国际学术期刊《科学》杂志。

研究人员研发了一种非常规的带通滤波器材料-粘弹性明胶-壳聚糖水凝胶阻尼器，以选择性地去除动态机械噪声伪影，其灵感来自蜘蛛体内的粘弹性表皮垫。水凝胶表现出与频率相关的相变，可产生抑制低频噪声的橡胶状态和传输高频信号所需的玻璃状态。它用作自适应通滤波器，能够从患者中获取高质量信号，同时最大限度地减少多余生物电子学信号处理。

据了解，生物电子学需要持续监测患者的机械和电生理信号。然而，这些信号总是包含由患者格外运动（例如大约30赫兹以下的步行和呼吸）造成的伪影。当前去除伪影的方法是使用带通滤波器的信号处理，这可能会导致信号丢失。

附：英文原文

Title: Cuticular pad–inspired selective frequency damper for nearly dynamic noise–free bioelectronics

Author: Byeonghak Park, Joo Hwan Shin, Jehyung Ok, Subin Park, Woojin Jung, Chanho Jeong, Seunghwan Choy, Young Jin Jo, Tae-il Kim

Issue&Volume: 2022-05-06

Abstract: Bioelectronics needs to continuously monitor mechanical and electrophysiological signals for patients. However, the signals always include artifacts by patients’ unexpected movement (such as walking and respiration under approximately 30 hertz). The current method to remove them is a signal process that uses a bandpass filter, which may cause signal loss. We present an unconventional bandpass filter material—viscoelastic gelatin-chitosan hydrogel damper, inspired by the viscoelastic cuticular pad in a spider—to remove dynamic mechanical noise artifacts selectively. The hydrogel exhibits frequency-dependent phase transition that results in a rubbery state that damps low-frequency noise and a glassy state that transmits the desired high-frequency signals. It serves as an adaptable passfilter that enables the acquisition of high-quality signals from patients while minimizing signal process for advanced bioelectronics.

DOI: abj9912

Source: https://www.science.org/doi/10.1126/science.abj9912