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| Notch锟脚号碉拷锟斤拷锟斤拷锟劫革拷细锟斤拷 |
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锟斤拷锟斤拷锟斤拷图片锟斤拷锟斤拷锟斤拷锟斤拷锟劫革拷细锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷织锟斤拷锟斤拷锟斤拷图锟斤拷锟斤拷些锟斤拷锟劫革拷细锟斤拷锟斤拷锟斤拷转录锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷转录锟斤拷锟斤拷锟斤拷锟斤拷钥锟絅otch效应锟斤拷Cbf-1锟斤拷shRNA锟斤拷转锟斤拷锟斤拷母锟较革拷锟斤拷锟街诧拷锟叫★拷锟斤拷锟斤拷锟斤拷脂锟斤拷锟斤拷锟叫ｏ拷锟斤拷锟斤拷锟斤拷8锟杰碉拷锟斤拷锟斤拷锟斤拷取锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟絅otch锟脚号讹拷锟斤拷锟斤拷锟斤拷锟劫凤拷锟斤拷锟斤拷锟斤拷锟斤拷MaSC锟斤拷锟斤拷展锟斤拷锟斤拷锟斤拷要锟斤拷锟矫★拷锟斤拷
锟斤拷锟斤拷锟窖э拷锟斤拷欠锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷俑锟较革拷锟斤拷锟組aSC锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷群锟戒，锟斤拷锟斤拷些锟斤拷锟街达拷锟劫斤拷锟剿讹拷锟节革拷细锟斤拷锟斤拷系锟街伙拷锟斤拷锟斤拷锟斤拷频锟斤拷芯锟斤拷锟斤拷锟�2008锟斤拷10锟斤拷9锟秸筹拷锟斤拷摹锟较革拷锟�—锟斤拷细锟斤拷锟斤拷锟斤拷Cell Stem Cell锟斤拷锟较ｏ拷锟斤拷锟皆澳达拷锟斤拷锟角碉拷Bouras锟饺匡拷学锟揭凤拷锟斤拷锟斤拷锟铰称ｏ拷锟斤拷锟角凤拷锟斤拷锟斤拷Notch锟脚猴拷途锟斤拷锟节碉拷锟斤拷锟介房锟斤拷细锟斤拷锟斤拷锟杰猴拷锟介房锟斤拷皮锟姐级锟斤拷锟斤拷锟斤拷锟斤拷锟接碉拷锟斤拷锟矫★拷
Notch锟斤拷一锟街匡拷膜锟斤拷锟斤拷锟藉，锟斤拷锟角广泛锟斤拷锟斤拷锟节革拷锟街讹拷锟斤拷细锟斤拷锟叫★拷Notch锟脚猴拷途锟斤拷锟斤拷锟节讹拷锟斤拷锟斤拷织锟斤拷细锟斤拷锟斤拷锟剿非筹拷锟斤拷要锟斤拷锟斤拷锟斤拷锟斤拷皮锟斤拷锟今经★拷血液锟酵硷拷锟斤拷取锟斤拷诒锟斤拷诘姆锟斤拷锟斤拷锟斤拷锟斤拷校锟斤拷芯锟斤拷锟皆憋拷锟斤拷郑锟斤拷贸锟組aSC锟斤拷锟斤拷细锟斤拷群锟斤拷锟叫的规范Notch效应锟斤拷Cbf-1锟斤拷锟斤拷锟斤拷锟铰革拷细锟斤拷锟斤拷锟皆碉拷锟斤拷强锟斤拷锟斤拷锟斤拷锟斤拷锟届常锟侥结构锟斤拷锟斤拷锟较凤拷锟街憋拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷Notch锟脚号讹拷锟斤拷锟斤拷锟斤拷MaSC锟斤拷展锟斤拷锟斤拷一锟斤拷锟斤拷锟矫★拷
同时锟斤拷学锟斤拷锟角伙拷锟斤拷锟街ｏ拷锟节碉拷锟斤拷锟斤拷皮锟斤拷ductal luminal epithelium锟斤拷锟叫ｏ拷Notch锟斤拷预锟饺硷拷锟筋，锟斤拷锟斤拷锟絅otch锟脚猴拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟絣uminal锟斤拷细锟斤拷锟斤拷luminal锟斤拷细锟斤拷锟斤拷锟斤拷展锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞达拷锟皆硷拷锟斤拷锟斤拷锟侥凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷为锟斤拷锟角的凤拷锟街斤拷示锟斤拷Notch锟脚猴拷锟斤拷MaSC锟斤拷luminal细锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟金到碉拷锟斤拷锟矫ｏ拷锟斤拷锟斤拷锟叫撅拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟絅otch锟斤拷锟筋将锟劫斤拷luminal锟斤拷细锟斤拷锟斤拷锟斤拷锟揭革拷锟铰猴拷转锟斤拷锟斤拷锟斤拷锟斤拷学锟斤拷 锟轿猴拷锟�/锟斤拷锟诫）
锟斤拷锟斤拷细锟斤拷—锟斤拷细锟斤拷锟斤拷锟斤拷Cell Stem Cell锟斤拷锟斤拷Vol 3, 429-441, 09 October 2008锟斤拷Toula Bouras, Jane E. Visvader锟斤拷
锟斤拷锟斤拷锟侥讹拷锟斤拷英锟侥ｏ拷
