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| AKAP锟斤拷锟阶讹拷锟侥硷拷锟绞达拷锟斤拷锟斤拷锟� |
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锟斤拷锟斤拷锟斤拷图片锟斤拷锟斤拷锟斤拷小锟斤拷锟斤拷锟揭硷拷细锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷学锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟缴拷锟斤拷锟轿狝KAP-Lbc锟斤拷锟斤拷色锟斤拷锟斤拷为锟斤拷原锟节憋拷堑锟斤拷锟�α-actinin锟斤拷锟斤拷色锟斤拷锟斤拷为锟剿憋拷锟斤拷铩ｏ拷锟�
锟斤拷锟洁病锟斤拷一锟街革拷锟接的硷拷锟斤拷锟斤拷锟斤拷也锟斤拷锟斤拷锟界范围锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷叩募锟斤拷锟街伙拷锟斤拷锟斤拷锟斤拷幕锟斤拷锟斤拷锟斤拷锟斤拷约锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷嗖★拷姆锟斤拷锟斤拷泄兀锟斤拷锟叫╋拷锟斤拷涌锟斤拷锟酵拷锟斤拷锟斤拷锟斤拷锟斤拷募锟较革拷锟斤拷锟斤拷藕糯锟斤拷浼讹拷锟斤拷锟斤拷谋锟斤拷募锟斤拷锟斤拷锟斤拷锟斤拷锟�β-锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷募锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟缴猴拷锟斤拷锟斤拷锟斤拷锟斤拷锟接讹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟脚猴拷通路锟斤拷锟斤拷锟皆硷拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷耍锟斤拷锟斤拷锟斤拷锟斤拷诙锟斤拷址锟斤拷锟斤拷锟斤拷氐牡锟斤拷锟斤拷锟缴的ｏ拷锟斤拷锟界动锟斤拷锟斤拷压锟斤拷锟斤拷锟斤拷锟侥わ拷锟斤拷锟斤拷龋锟斤拷锟叫╋拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟窖癸拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞达拷冉锟斤拷锟斤拷锟节凤拷锟斤拷水平锟较ｏ拷锟绞达拷锟脚号ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟截伙拷锟斤拷锟斤拷呓锟斤拷锟斤拷鸭锟较革拷锟斤拷锟角匡拷锟斤拷樱锟組yocyte Enhancer Factor MEF锟斤拷锟斤拷转录锟斤拷锟筋。
锟斤拷锟叫撅拷锟斤拷锟斤拷锟斤拷锟斤拷膜锟斤拷转录锟斤拷锟斤拷MEF2之锟斤拷锟斤拷藕锟斤拷诓锟斤拷锟斤拷锟斤拷锟斤拷锟绞达拷锟斤拷锟斤拷薪锟斤拷锟斤拷锟斤拷谋洌琈EF2锟侥伙拷锟斤拷锟杰碉拷锟斤拷锟斤拷锟介蛋锟斤拷锟斤拷锟斤拷锟斤拷酶锟斤拷histone deacetylase HDAC锟斤拷锟斤拷锟接的匡拷锟狡★拷锟斤拷些酶锟斤拷锟斤拷去锟斤拷小锟斤拷锟斤拷锟介蛋锟阶碉拷锟斤拷锟斤拷锟斤拷锟斤拷锟接讹拷锟劫斤拷染色锟斤拷浓锟斤拷锟斤拷转录锟斤拷锟狡★拷锟介蛋锟斤拷锟斤拷锟斤拷锟斤拷酶锟斤拷锟斤拷锟结化锟斤拷使锟斤拷锟斤拷锟角达拷锟斤拷MEF2锟侥斤拷锟斤拷蟹锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟脚凤拷锟斤拷锟斤拷MEF2去锟斤拷锟斤拷锟斤拷媒锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟阶硷拷锟斤拷佣锟斤拷俳锟斤拷锟斤拷路蚀锟侥伙拷锟斤拷锟斤拷铩ｏ拷锟斤拷锟斤拷锟斤拷锟铰凤拷锟斤拷锟矫恳伙拷锟斤拷锟斤拷玫锟斤拷撕芎玫亩锟斤拷澹拷锟斤拷强锟窖э拷叶锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟较筹拷一锟斤拷锟斤拷态细锟斤拷锟脚号硷拷锟斤拷锟斤拷锟教的伙拷锟斤拷却知之锟斤拷锟劫★拷
锟斤拷2008锟斤拷10锟斤拷24锟秸筹拷锟斤拷摹锟斤拷锟斤拷锟较革拷锟斤拷锟斤拷锟�Molecular Cell锟斤拷锟较ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷士锟斤拷锟叫撅拷小锟介发锟斤拷锟斤拷锟铰称ｏ拷锟斤拷锟角凤拷锟斤拷锟斤拷锟斤拷A锟酵硷拷酶锚锟斤拷锟斤拷锟阶ｏ拷A-kinase anchoring protein锟斤拷AKAP锟斤拷锟节肥达拷锟斤拷募锟较革拷锟斤拷械玫锟斤拷锟斤拷锟斤拷兀锟酵拷锟斤拷锟斤拷锟斤拷准锟矫革拷锟斤拷锟斤拷锟斤拷锟斤拷锟矫革拷锟斤拷锟斤拷锟斤拷峤伙拷锟斤拷锟斤拷锟斤拷约锟斤拷锟斤拷锟斤拷锟斤拷酶锟斤拷锟较筹拷锟脚号革拷锟斤拷锟藉，AKAP锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫凤拷锟斤拷锟剿伙拷跃锟斤拷锟矫★拷锟斤拷锟侥硷拷细锟斤拷锟叫ｏ拷AKAP-Lbc锟斤拷锟斤拷PKA锟斤拷PKC锟斤拷支锟杰碉拷锟阶碉拷锟斤拷锟矫ｏ拷锟斤拷锟斤拷锟节碉拷锟斤拷锟斤拷酶-锟斤拷锟阶硷拷酶D锟斤拷PKD1锟斤拷锟侥硷拷锟筋。锟斤拷学锟揭凤拷锟街ｏ拷AKAP-Lbc锟斤拷通锟斤拷一锟斤拷PKD/HDAC5/MEF2路锟斤拷锟斤拷锟斤拷强锟脚号癸拷锟绞★拷
锟斤拷学锟斤拷锟角憋拷示锟斤拷锟斤拷锟杰大部分碉拷锟叫撅拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫★拷锟斤拷锟侥硷拷锟斤拷锟叫的ｏ拷锟斤拷锟角讹拷锟斤拷位锟斤拷锟斤拷锟侥硷拷锟绞大疾诧拷锟侥伙拷锟竭碉拷锟斤拷锟斤拷锟斤拷织锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭仓э拷锟斤拷锟叫★拷锟斤拷锟叫撅拷锟斤拷锟斤拷锟斤拷锟轿伙拷锟斤拷叻直锟斤拷锟揭晃�46锟斤拷锟斤拷锟皆猴拷一位62锟斤拷女锟皆★拷锟斤拷锟斤拷锟绞続KAP-Lbc使锟斤拷锟阶硷拷酶D锟斤拷锟斤拷锟斤拷锟斤拷祝锟斤拷锟斤拷锟绞癸拷榈帮拷锟斤拷锟斤拷锟斤拷锟阶拷锟矫窰DAC5锟斤拷锟结化锟斤拷锟斤拷锟劫斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟秸猴拷锟介蛋锟斤拷锟斤拷锟斤拷锟斤拷转锟斤拷酶锟斤拷锟皆的斤拷锟斤拷锟斤拷锟斤拷锟斤拷MEF2转录锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷蚀锟侥凤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷锟侥硷拷锟绞达拷锟斤拷一锟街非筹拷锟秸憋拷锟街⒆达拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟街�1999锟斤拷锟斤拷锟斤拷荩锟饺拷锟斤拷约14%-18%锟侥筹拷锟斤拷锟杰碉拷锟斤拷一锟斤拷症锟斤拷影锟届。锟斤拷耍锟教斤拷锟紸KAP-Lbc/PKD/HDAC5锟脚猴拷路锟斤拷锟斤拷锟斤拷锟矫非筹拷锟斤拷要锟斤拷锟斤拷锟斤拷学锟斤拷 锟轿猴拷锟�/锟斤拷锟诫）
锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷Molecular Cell锟斤拷锟斤拷Volume 32, Issue 2, 169-179, 24 October 2008锟斤拷Graeme K. Carnegie, John D. Scott锟斤拷
锟斤拷锟斤拷锟侥讹拷锟斤拷英锟侥ｏ拷
