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锟斤拷锟斤拷锟斤拷锟捷达拷学锟缴斤拷山锟斤拷校锟斤拷一锟斤拷锟叫撅拷锟斤拷员锟斤拷前锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷微RNA小锟斤拷锟斤拷取锟斤拷一锟街匡拷锟斤拷锟铰帮拷锟斤拷转录锟斤拷锟接ｏ拷锟缴癸拷锟斤拷实锟斤拷锟斤拷皮锟斤拷细锟斤拷转锟斤拷为“锟秸碉拷锟洁功锟杰革拷细锟斤拷(iPS细锟斤拷)”锟斤拷锟斤拷锟斤拷锟斤拷姆锟斤拷锟斤拷锟�4锟斤拷12锟秸的★拷锟斤拷然—锟斤拷锟斤技锟斤拷锟斤拷锟斤拷Nature Biotechnology 锟斤拷锟斤拷志锟斤拷锟斤拷锟斤拷稀锟�
iPS细锟斤拷锟斤拷指锟斤拷细锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷“锟斤拷锟铰憋拷锟斤拷”锟斤拷锟截归到锟斤拷胎锟斤拷细锟斤拷锟斤拷状态锟斤拷锟接讹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷胎锟斤拷细锟斤拷锟侥分伙拷锟斤拷锟斤拷锟斤拷锟斤拷学锟斤拷锟斤拷为锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷全锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷陌锟饺拷愿锟斤拷叩锟絠PS细锟斤拷锟斤拷
锟斤拷皮锟斤拷细锟斤拷锟斤拷锟斤拷“锟斤拷锟斤拷”使锟斤拷锟轿猧PS细锟斤拷锟芥及4锟斤拷转录锟斤拷锟接的憋拷锟斤。目前锟斤拷锟矫的凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷转录锟斤拷锟斤拷锟斤拷为锟斤拷锟藉将锟斤拷锟斤拷锟斤拷4锟斤拷转录锟斤拷锟接的伙拷锟斤拷注锟斤拷皮锟斤拷锟侥筹拷锟斤拷维细锟斤拷锟叫ｏ拷锟斤拷锟斤拷锟斤拷3锟斤拷转录锟斤拷锟接匡拷锟斤拷锟秸凤拷锟斤拷症锟斤拷一锟斤拷锟教讹拷锟斤拷锟斤拷锟斤拷锟斤拷iPS细锟斤拷锟斤拷应锟斤拷前锟斤拷锟斤拷
锟斤拷锟捷达拷学锟缴斤拷山锟斤拷校锟侥匡拷锟斤拷小锟介尝锟斤拷锟斤拷微RNA锟斤拷锟斤拷取锟斤拷锟斤拷锟斤拷一锟斤拷转录锟斤拷锟接ｏ拷锟斤拷锟斤拷3锟斤拷转录锟斤拷锟接的伙拷锟斤拷锟斤拷锟斤拷锟斤拷转录锟斤拷锟斤拷锟斤拷锟诫。实锟斤拷锟叫ｏ拷锟斤拷锟角斤拷微RNA锟斤拷锟斤拷锟斤拷脂锟斤拷使锟斤拷锟斤拷锟剿筹拷锟斤拷锟斤拷锟斤拷锟斤拷锟轿革拷锟斤拷锟较革拷锟侥わ拷锟斤拷锟较革拷锟斤拷小锟�
锟桔察发锟街ｏ拷微RNA锟斤拷锟斤拷锟斤拷锟阶硷拷锟斤拷臃锟斤拷锟�“锟秸碉拷”锟斤拷锟杰ｏ拷锟斤拷锟斤拷锟斤拷锟街革拷锟斤拷锟绞碉拷锟斤拷锟狡わ拷锟斤拷锟斤拷锟轿革拷锟斤拷锟斤拷苑只锟轿碉拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷偷锟较革拷锟斤拷锟�
锟斤拷锟斤拷锟斤拷锟侥匡拷锟较革拷锟斤拷锟斤拷锟窖э拷锟斤拷薏锟斤拷锟�·锟斤拷锟斤拷锟斤拷锟剿碉拷锟�“锟斤拷锟斤拷锟斤拷锟斤拷微RNA小锟斤拷锟接匡拷锟斤拷细锟斤拷锟侥凤拷锟斤拷锟斤拷锟斤拷未锟斤拷锟侥革拷细锟斤拷锟斤拷锟斤拷学锟叫撅拷锟叫斤拷锟斤拷锟斤拷锟斤拷要锟侥斤拷色锟斤拷”锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷锟叫撅拷锟截碉拷锟斤拷锟狡斤拷微RNA锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫凤拷锟斤拷锟斤拷锟矫的伙拷锟狡ｏ拷锟斤拷锟斤拷锟斤拷一锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷微RNA锟斤拷全取锟斤拷锟斤拷锟斤拷4锟斤拷转录锟斤拷锟斤拷锟斤拷锟斤拷iPS细锟斤拷锟侥凤拷锟斤拷锟斤拷 锟斤拷锟斤拷源锟斤拷锟狡硷拷锟秸憋拷锟斤拷
锟斤拷锟斤拷锟斤拷然—锟斤拷锟斤技锟斤拷锟斤拷锟斤拷
Nature Biotechnology 锟斤拷锟斤拷doi:10.1038/nbt.1535锟斤拷Robert L Judson锟斤拷Robert Blelloch锟斤拷
锟斤拷锟斤拷锟侥讹拷锟斤拷英锟侥ｏ拷
锟斤拷锟斤拷然—锟斤拷锟斤技锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷摘要
